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PopGen Fishbowl is an agent-based population genetics simulation. The program contains the tools to conduct virtual experiments violating all the assumptions of Hardy-Weinberg theory. You can explore the effects of: 1- Small population size Genetic Drift 2- Selection 3- Mutation 4- Migration 5- Non-random mating Some basic population biology is also demonstrated such as, logistic population growth and the Allee Effect. HOW IT WORKS The agents are fish in a small pond. When fish come together and are of opposite sex they may breed, producing offspring following mendelian inheritance patterns. The model simulates overlapping generations, with reproduction occurring whenever fish may meet. The population should grow and hover around 100 fish. All three colors should persist, though the frequency of the R allele may drift over time and given enough time may become fixed at 100% or extinct. Experimental Variables Selection Sets the relative fitness of each genotype. Selection is imposed on the juveniles Note: you can simulate selection against a dominant or recessive allele by making the relative fitness of Rr equal to one of the homozygotes. Migration Migration-rate sets the probability that a fish in the pond is replaced by one from another pond. Migrant-Freq-R sets the frequency of R allele in the migrant population. Mutation This calls a probability that an allele in a juvenile will mutate. Red alleles mutating to white and white to red are called separately. Non-random Mating If assortment 0, they will be more likely to mate with the same color fish inbreeding. Because of this, there are several things which might prevent the population from behaving as expected. For example: If Init-N is low, the fish may not find a suitable partner and breed fast enough and the population may die out Allee effect. THINGS TO TRY This model is designed as a teaching tool. Pedagogically, this may be preferable to the model exporting data. One approach would be to lead students through an experiment e. EXTENDING THE MODEL With just the controls to tweak the five conditions for Hardy-Weinberg equilibrium it is hard to fit this model on a small screen. For example, allele fixation is not just a value or plot going to 0 or 1. The fact that it is an actual simulation means that there is variation in results, which is biologically realistic. RELATED MODELS The most similar model I know of is the commercially available Evobeaker ®. Related Netlogo models I have found include: Models in the library Evolution folder Related Netlogo community models include: Bug Hunt Evolution CREDITS AND REFERENCES PopGen Fishbowl 1. Wilensky and all who created Netlogo, for creating an environment in which a code-phobic professor can work.